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You may be able to detect forever chemicals in your water soon

When Sandia National Laboratories scientists Ryan Davis and Nathan Bays set out to find a better way to absorb and degrade PFAS in water sources, they kept running into the same issue: Detecting the chemicals in samples took too long.

So, they came up with their own solution.

They've developed a faster, cheaper way to test for PFAS.

Nathan Bays adds a tiny adsorbent particle to a solution containing an analyte of interest (e.g., PFAS) for analysis using the ISA-DESI technique at Sandia National Laboratories. [Credit: Photo by Craig Fritz/Sandia]

 

 

 

 

The problem of PFAS and solving it
PFAS, or per-and polyfluoroalkyl substances, are commonly called forever chemicals because they don't break down naturally in the environment. They can move through soil and water and build up in wildlife and humans.

Davis, a chemist, has spent years developing technologies that can eliminate PFAS on both large and small scales. However, that research has been time consuming. Depending on the concentration, it can take hours to days to detect PFAS in a single sample.

"A common complaint of ours and others who are doing PFAS analysis is that it's slow and can be costly depending on the technology," Davis said.

Traditional testing requires repetitive extraction, concentration, and processing.

It starts with a liter or more of liquid suspected to contain PFAS. The liquid is forced through a cartridge to extract the PFAS. The collected PFAS is then added to a smaller volume of water, and the process is repeated with new cartridges until enough PFAS is concentrated for detection.

The process is not only time consuming but also costly. Cartridges can cost several hundred dollars each.

That process not only slows research and development but puts testing out of reach for the average person.

An adsorbent particle containing the analyte of interest (e.g., PFAS) is sprayed with charged droplets that splash off the surface and are captured by a metal tube and carried into a mass spectrometer for analysis. This process is known as desorption electrospray ionization. [Credit: Photo by Craig Fritz/Sandia]

 

 

 

 

"We want a technology that can be broadly accessible, not only for researchers but for the broader public and government," Davis said. "It will allow regulators to track PFAS in the environment and for people to test their own tap water."

A new way to detect PFAS
Davis and Sandia postdoctoral researcher Nathan Bays have developed that technology.

The pair stumbled onto the approach while experimenting with a mass spectrometer and a technique called desorption electrospray ionization, or DESI. The process uses electrically charged droplets sprayed at the surface of an adsorbent that ionizes only the target chemical, not the adsorbent itself.

Bays and Davis said the results were unexpected.

"We had toyed with the idea of using DESI to confirm the presence of PFAS on adsorbent materials," Davis said. "When we did some preliminary testing, not only did we confirm the presence of PFAS, but we noticed that we got results well beyond our standard analysis."

"At this point, it became very clear we had an opportunity to push further on this work," Bays said. "One step at a time, we went from just being able to see PFAS at parts-per-million to levels at parts-per-billion, and finally low parts-per-trillion."

Davis and Bays' technique starts with an adsorbent about the size of a Rice Krispie. The adsorbent is placed in a solution for testing. Three minutes later, it is removed and placed in front of a mass spectrometer where it is sprayed with electrically charged droplets. The droplets remove PFAS from the adsorbent and carry it into the mass spectrometer, where it is analyzed for PFAS concentration and type.

The entire process can take as little as five minutes.

The ISA-DESI analysis procedure. [Credit: Graphic by Ryan Davis and Nathan Bays/Sandia]

 

 

"It's one of those outcomes that wasn't exactly planned as we had initially envisioned it," Davis said. "It was surprising to see the concentration of PFAS so clearly. That may be why it hadn't been done before. It was just unexpected."

The pair has published details of the process in hopes it can be commercialized for widespread use. They also hope it can be developed to tackle other environmental pollutants besides PFAS and used for environmental analytics and testing such as off-gassing measurements tied to Sandia's nuclear deterrence work.

"It could help researchers understand the system's environment and the off-gassing of chemicals in certain work," Davis said. "While our first phase worked with liquid, our more recent work has delved into the gas phase."

Why they do it
Both Davis and Bays are passionate about this technology and PFAS remediation. Developing the new test is just a small part of the broader work they do aimed at reducing PFAS pollution.

Nathan Bays prepares sample solutions to test the ISA-DESI technique used to detect PFAS at Sandia National Laboratories. [Credit: Photo by Craig Fritz/Sandia]

 

 

 

 

"I've been working on this specific project since I joined Sandia two-and-a-half years ago," Bays said. "My whole career has evolved around environmental remediation, so this was a natural fit. I'm a big outdoors person. My wife and I like to go out in nature, and we don't like to see our world be polluted like this."

One of the biggest focuses of PFAS remediation has been at U.S. Air Force bases, where soil and groundwater have been impacted by the long-term use of firefighting foam.

Davis's big goal, however, is to give people more power over their health.

"More and more research shows that PFAS can have negative outcomes at even low concentrations, so detecting at those low concentrations is key," Davis said.

Source: Sandia National Laboratories

Published March 2026

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